Lactate dehydrogenase 5 expression in operable colorectal cancer: strong association with survival and activated vascular endothelial growth factor pathway--a report of the Tumour Angiogenesis Research Group.

PURPOSE: Lactate dehydrogenase 5 (LDH-5) regulates, under hypoxic conditions, the anaerobic transformation of pyruvate to lactate for energy acquisition. Several studies have shown that serum LDH may be an ominous prognostic marker in malignant tumors. The clinical significance of tissue LDH-5, how...

Descripció completa

Dades bibliogràfiques
Autors principals: Koukourakis, M, Giatromanolaki, A, Sivridis, E, Gatter, K, Harris, A
Format: Journal article
Idioma:English
Publicat: 2006