THE RING EXPANSION OF PENAMS TO CEPHAMS - A POSSIBLE BIOMIMETIC PROCESS
Reaction of a 2β-bromomethyl penam with triphenyltin hydride gave, via ring expansion of the derived 2β-methyl radical, the corresponding cepham system; a similar process may be in operation during the biosynthetic ring expansion of penicillin N to deacetoxycephalasporin C.1. © 1988.
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
1988
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