Parathyroid hormone-related protein is induced by hypoxia and promotes expression of the differentiated phenotype of human articular chondrocytes.

PTHrP (parathyroid hormone-related protein) is crucial for normal cartilage development and long bone growth and acts to delay chondrocyte hypertrophy and terminal differentiation in the growth plate. After growth plate closure adult HACs (human articular chondrocytes) still produce PTHrP, suggestin...

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Bibliographic Details
Main Authors: Pelosi, M, Lazzarano, S, Thoms, B, Murphy, C
Format: Journal article
Language:English
Published: 2013