Convergent transcription induces transcriptional gene silencing in fission yeast and mammalian cells.

We show that convergent transcription induces transcriptional gene silencing (TGS) in trans for both fission yeast and mammalian cells. This method has advantages over existing strategies to induce gene silencing. Previous studies in fission yeast have characterized TGS as a cis-specific process inv...

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Bibliographic Details
Main Authors: Gullerova, M, Proudfoot, N
Format: Journal article
Language:English
Published: 2012