A GMP protocol for the manufacture of Tregs for clinical application

Infusion of regulatory T cells is a promising therapeutic strategy in organ transplantation to modulate the immune system, prevent rejection, minimize the need for pharmaceutical immunosuppression, and improve long-term transplant outcomes. Here we describe a GMP-compliant method we have used for th...

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Bibliographic Details
Main Authors: O'Neil, A, Brook, M, Abdul-Wahab, S, Hester, J, Lombardi, G, Issa, F
Format: Book section
Language:English
Published: Humana Press 2022