Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites

Chimeric Plasmodium falciparum parasites expressing Plasmodium vivax circumsporozoite protein fail to produce salivary gland sporozoites

<strong>Background</strong> Rodent malaria parasites where the gene encoding circumsporozoite protein (CSP) has been replaced with csp genes from the human malaria parasites, Plasmodium falciparum or Plasmodium vivax, are used as pre-clinical tools to evaluate CSP vaccines in vivo. These...

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Detalhes bibliográficos
Main Authors: Marin-Mogollon, C, Van Pul, F, Miyazaki, S, Imai, T, Ramesar, J, Salman, A, Winkel, B, Othman, A, Kroeze, H, Chevalley-Maurel, S, Reyes-Sandoval, A, Roestenberg, M, Franke-Fayard, B, Janse, C, Khan, S
Formato: Journal article
Idioma:English
Publicado em: BioMed Central 2018

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