Colicins exploit native disorder to gain cell entry: a hitchhiker's guide to translocation.

The translocation of protein toxins into a cell relies on a myriad of protein-protein interactions. One such group of toxins are enzymatic E colicins, protein antibiotics produced by Escherichia coli in times of stress. These proteins subvert ordinary nutrient uptake mechanisms to enter the cell and...

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Bibliographic Details
Main Authors: Bonsor, D, Meenan, N, Kleanthous, K
Format: Journal article
Language:English
Published: 2008