Vascular peptide endothelin-1 links fat accumulation with alterations of visceral adipocyte lipolysis.

OBJECTIVE: Visceral obesity increases risk of insulin resistance and type 2 diabetes. This may partly be due to a region-specific resistance to insulin's antilipolytic effect in visceral adipocytes. We investigated whether adipose tissue releases the vascular peptide endothelin-1 (ET-1) and wh...

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Bibliographic Details
Main Authors: van Harmelen, V, Eriksson, A, Aström, G, Wåhlén, K, Näslund, E, Karpe, F, Frayn, K, Olsson, T, Andersson, J, Rydén, M, Arner, P
Format: Journal article
Language:English
Published: 2008