Hierarchically related lineage-restricted fates by multipotent hematopoietic stem cells

Rare multipotent haematopoietic stem cells (HSCs) in adult bone marrow with extensive self-renewal potential can efficiently replenish all myeloid and lymphoid blood cells1, securing long-term multilineage reconstitution after physiological and clinical challenges such as chemotherapy and haematopoi...

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Bibliographic Details
Main Authors: Carrelha, C, Meng, Y, Kettyle, L, Luis, T, Norfo, R, Alcolea, V, Boukarabila, H, Grasso, F, Gambardella, A, Grover, A, Högstrand, K, Lord, A, Sanjuan-Pla, A, Woll, P, Nerlov, C, Jacobsen, S
Format: Journal article
Published: Nature Publishing Group 2018