Hierarchically related lineage-restricted fates by multipotent hematopoietic stem cells

Hierarchically related lineage-restricted fates by multipotent hematopoietic stem cells

Rare multipotent haematopoietic stem cells (HSCs) in adult bone marrow with extensive self-renewal potential can efficiently replenish all myeloid and lymphoid blood cells1, securing long-term multilineage reconstitution after physiological and clinical challenges such as chemotherapy and haematopoi...

Ausführliche Beschreibung

Bibliographische Detailangaben
Hauptverfasser:	Carrelha, C, Meng, Y, Kettyle, L, Luis, T, Norfo, R, Alcolea, V, Boukarabila, H, Grasso, F, Gambardella, A, Grover, A, Högstrand, K, Lord, A, Sanjuan-Pla, A, Woll, P, Nerlov, C, Jacobsen, S
Format:	Journal article
Veröffentlicht:	Nature Publishing Group 2018

Ähnliche Einträge

Erythropoietin guides multipotent hematopoietic progenitor cells toward an erythroid fate.
von: Grover, A, et al.
Veröffentlicht: (2014)

Single cell RNA sequencing reveals molecular and functional platelet bias of aged hematopoietic stem cells
von: Nerlov, C, et al.
Veröffentlicht: (2016)

Antagonism between C/EBPbeta and FOG in eosinophil lineage commitment of multipotent hematopoietic progenitors.
von: Querfurth, E, et al.
Veröffentlicht: (2000)

FLT3 expression initiates in fully multipotent mouse hematopoietic progenitor cells.
von: Buza-Vidas, N, et al.
Veröffentlicht: (2011)

Hematopoietic lineage diversification, simplified
von: Drissen, R, et al.
Veröffentlicht: (2016)

Loss of endothelial membrane KIT ligand affects systemic KIT ligand levels but not bone marrow hematopoietic stem cells
von: Matsuoka, S, et al.
Veröffentlicht: (2023)

DNA methylation protects hematopoietic stem cell multipotency from myeloerythroid restriction.
von: Bröske, A, et al.
Veröffentlicht: (2009)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy
von: Sanjuan-Pla, A, et al.
Veröffentlicht: (2013)

To bi or not to bi: Acute erythroid leukemias and hematopoietic lineage choice
von: di Genua, C, et al.
Veröffentlicht: (2021)

Delineating the cellular pathways of hematopoietic lineage commitment.
von: Luc, S, et al.
Veröffentlicht: (2008)

Epigenetic programming defines haematopoietic stem cell fate restriction
von: Meng, Y, et al.
Veröffentlicht: (2023)

Platelet-biased stem cells reside at the apex of the haematopoietic stem-cell hierarchy.
von: Sanjuan-Pla, A, et al.
Veröffentlicht: (2013)

Lineage-biased hematopoietic stem cells are regulated by distinct niches
von: Pinho, S, et al.
Veröffentlicht: (2018)

Inference, validation, and dynamic modeling of transcription networks in multipotent hematopoietic cells.
von: Soneji, S, et al.
Veröffentlicht: (2007)

Alternative platelet differentiation pathways initiated by nonhierarchically related hematopoietic stem cells
von: Carrelha, J, et al.
Veröffentlicht: (2024)

Molecular evidence for hierarchical transcriptional lineage priming in fetal and adult stem cells and multipotent progenitors.
von: Månsson, R, et al.
Veröffentlicht: (2007)

Cell-intrinsic depletion of Aml1-ETO-expressing pre-leukemic hematopoietic stem cells by K-Ras activating mutation.
von: Di Genua, C, et al.
Veröffentlicht: (2019)

Pontin is essential for murine hematopoietic stem cell survival.
von: Bereshchenko, O, et al.
Veröffentlicht: (2012)

FLT3-ITDs Introduce a Myeloid Differentiation and Transformation Bias to Multipotent Lympho-Myeloid Progenitors
von: Mead, A, et al.
Veröffentlicht: (2011)

Hematopoietic stem cell expansion precedes the generation of committed myeloid leukemia-initiating cells in C/EBPalpha mutant AML.
von: Bereshchenko, O, et al.
Veröffentlicht: (2009)

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential
von: Luc, S, et al.
Veröffentlicht: (2012)

The earliest thymic T cell progenitors sustain B cell and myeloid lineage potential.
von: Luc, S, et al.
Veröffentlicht: (2012)

MicroRNAs Modulate Hematopoietic Lineage Differentiation
von: Lodish, Harvey F., et al.
Veröffentlicht: (2004)

FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors
von: Mancini, E, et al.
Veröffentlicht: (2012)

FOG-1 and GATA-1 act sequentially to specify definitive megakaryocytic and erythroid progenitors.
von: Mancini, E, et al.
Veröffentlicht: (2012)

A lineage of myeloid cells independent of myb and hematopoietic stem cells
von: Schulz, C, et al.
Veröffentlicht: (2012)

A lineage of myeloid cells independent of Myb and hematopoietic stem cells
von: Perdiguero, E, et al.
Veröffentlicht: (2012)

Rb regulates fate choice and lineage commitment in vivo
von: Calo, Eliezer, et al.
Veröffentlicht: (2012)

A lineage of myeloid cells independent of Myb and hematopoietic stem cells.
von: Schulz, C, et al.
Veröffentlicht: (2012)

Perivascular niche cells sense thrombocytopenia and activate hematopoietic stem cells in an IL-1 dependent manner
von: Luis, TC, et al.
Veröffentlicht: (2023)

Metabolic and genetic factors guiding hematopoietic cell fate
von: Do, Brian Tshao
Veröffentlicht: (2023)

Transcriptional networks regulating hematopoietic cell fate decisions.
von: Loose, M, et al.
Veröffentlicht: (2007)

Effects of micro and nanotopography on hematopoietic cell fate decision
von: Lim, Kuan Chien.
Veröffentlicht: (2011)

Stem cell biology is population biology: differentiation of hematopoietic multipotent progenitors to common lymphoid and myeloid progenitors.
von: Mangel, M, et al.
Veröffentlicht: (2013)

Dicer is required for neural stem cell multipotency and lineage progression during cerebral cortex development.
von: Saurat, N, et al.
Veröffentlicht: (2013)

Early chromatin shaping predetermines multipotent vagal neural crest into neural, neuronal and mesenchymal lineages
von: Ling, ITC, et al.
Veröffentlicht: (2019)

FLT3-ITDs instruct a myeloid differentiation and transformation bias in lymphomyeloid multipotent progenitors.
von: Mead, A, et al.
Veröffentlicht: (2013)

Global genetic regulatory networks controlling hematopoietic cell fates.
von: Loose, M, et al.
Veröffentlicht: (2006)

Distinct myeloid progenitor differentiation pathways identified through single cell RNA sequencing
von: Drissen, R, et al.
Veröffentlicht: (2016)

Biological and molecular evidence for existence of lymphoid-primed multipotent progenitors.
von: Luc, S, et al.
Veröffentlicht: (2007)