AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.

AMP-activated protein kinase phosphorylates cardiac troponin I and alters contractility of murine ventricular myocytes.

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RATIONALE: AMP-activated protein kinase (AMPK) is an important regulator of energy balance and signaling in the heart. Mutations affecting the regulatory γ2 subunit have been shown to cause an essentially cardiac-restricted phenotype of hypertrophy and conduction disease, suggesting a specific role...

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Bibliographic Details
Main Authors: Oliveira, S, Zhang, Y, Solis, R, Isackson, H, Bellahcene, M, Yavari, A, Pinter, K, Davies, J, Ge, Y, Ashrafian, H, Walker, J, Carling, D, Watkins, H, Casadei, B, Redwood, C
Format: Conference item
Published: 2012

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