A practical asymmetric synthesis of homochiral alpha-arylglycines

Enantioselective reduction of a series of substituted aryl trichloromethyl ketones with the CBS-catecholborane reagent afforded homochiral aryl trichloromethyl carbinols which have been elaborated to give homochiral α-arylglycines in high e.e. © 2001 Elsevier Science Ltd.

Bibliographic Details
Main Authors: Mellin-Morliere, C, Aitken, D, Bull, S, Davies, S, Husson, H
Format: Journal article
Language:English
Published: 2001