Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study.

BACKGROUND: Nitric oxide has been implicated in tumour angiogenesis and in the maintaining of vasodilator tone of tumour blood vessels. The tumour vascular effects of inhibition of nitric-oxide synthesis have not been investigated in patients with cancer. METHODS: Seven women and 11 men (12 with non...

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Bibliographic Details
Main Authors: Ng, Q, Goh, V, Milner, J, Stratford, MR, Folkes, L, Tozer, G, Saunders, M, Hoskin, P
Format: Journal article
Language:English
Published: 2007