Effect of nitric-oxide synthesis on tumour blood volume and vascular activity: a phase I study.
BACKGROUND: Nitric oxide has been implicated in tumour angiogenesis and in the maintaining of vasodilator tone of tumour blood vessels. The tumour vascular effects of inhibition of nitric-oxide synthesis have not been investigated in patients with cancer. METHODS: Seven women and 11 men (12 with non...
Main Authors: | , , , , , , , |
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Format: | Journal article |
Language: | English |
Published: |
2007
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