Covalent strategies for targeting messenger and non-coding RNAs: an updated review on siRNA, miRNA and antimiR conjugates

Oligonucleotide-based therapy has become an alternative to classical approaches in the search of novel therapeutics involving gene-related diseases. Several mechanisms have been described in which demonstrate the pivotal role of oligonucleotide for modulating gene expression. Antisense oligonucleoti...

Disgrifiad llawn

Manylion Llyfryddiaeth
Prif Awduron: Grijalvo, S, Alagia, A, Jorge, A, Eritja, R
Fformat: Journal article
Iaith:English
Cyhoeddwyd: MDPI 2018