Covalent strategies for targeting messenger and non-coding RNAs: an updated review on siRNA, miRNA and antimiR conjugates

Oligonucleotide-based therapy has become an alternative to classical approaches in the search of novel therapeutics involving gene-related diseases. Several mechanisms have been described in which demonstrate the pivotal role of oligonucleotide for modulating gene expression. Antisense oligonucleoti...

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Autori principali: Grijalvo, S, Alagia, A, Jorge, A, Eritja, R
Natura: Journal article
Lingua:English
Pubblicazione: MDPI 2018