Kinetics of abacavir-induced remodelling of the major histocompatibility complex class I peptide repertoire

Kinetics of abacavir-induced remodelling of the major histocompatibility complex class I peptide repertoire

Abacavir hypersensitivity syndrome can occur in individuals expressing the HLA-B*57:01 major histocompatibility complex class I allotype when utilising the drug abacavir as a part of their anti-retroviral regimen. The drug is known to bind within the HLA-B*57:01 antigen binding cleft, leading to the...

Полное описание

Библиографические подробности
Главные авторы:	Illing, PT, van Hateren, A, Darley, R, Croft, NP, Mifsud, NA, King, S, Kostenko, L, Bharadwaj, M, McCluskey, J, Elliott, T, Purcell, AW
Формат:	Journal article
Язык:	English
Опубликовано:	Frontiers Media 2021

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