Modulation of the PD-1 pathway by inhibitory antibody superagonists
<p>In metozoans, most of the key events that lead to cell activation and inhibition are controlled by tyrosine phosphorylation. Extracellular signals are transmitted by membrane bound receptors, which have intrinsic kinase activity or themselves recruit intracellular kinases to specialised inh...
Auteur principal: | Akkaya, B |
---|---|
Autres auteurs: | Davis, S |
Format: | Thèse |
Langue: | English |
Publié: |
2012
|
Sujets: |
Documents similaires
-
Second generation superagonistic anti-PD-1 antibodies
par: Yu, SY
Publié: (2019) -
Inhibitory superagonistic antibodies as novel therapeutics
par: Donat, RF
Publié: (2023) -
In vivo characterization of inhibitory anti-PD-1 antibody superagonists
par: Akkaya, B, et autres
Publié: (2011) -
Regulation of human and mouse bystander T cell activation responses by PD-1
par: Catherine T. Le, et autres
Publié: (2023-09-01) -
Functional and mechanistic advantage of the use of a bifunctional anti-PD-L1/IL-15 superagonist
par: Jeffrey Schlom, et autres
Publié: (2020-05-01)