Asymmetric switching in a homodimeric ABC transporter: a simulation study

ABC transporters are a large family of membrane proteins involved in a variety of cellular processes, including multidrug and tumor resistance and ion channel regulation. Advances in the structural and functional understanding of ABC transporters have revealed that hydrolysis at the two canonical nu...

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Bibliographic Details
Main Authors: Aittoniemi, J, De Wet, H, Ashcroft, F, Sansom, MS
Format: Journal article
Language:English
Published: Public Library of Science 2010