Asymmetric switching in a homodimeric ABC transporter: a simulation study

ABC transporters are a large family of membrane proteins involved in a variety of cellular processes, including multidrug and tumor resistance and ion channel regulation. Advances in the structural and functional understanding of ABC transporters have revealed that hydrolysis at the two canonical nu...

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Détails bibliographiques
Auteurs principaux: Aittoniemi, J, De Wet, H, Ashcroft, F, Sansom, MS
Format: Journal article
Langue:English
Publié: Public Library of Science 2010