Single-cell immune survey identifies a novel pathogenic role for T cells in anti-NMDA receptor encephalitis

We performed single-cell RNA and immune receptor repertoire sequencing of an N-methyl-D-aspartate receptor encephalitis (NMDARE) patient in relapse and remission states, as well as an autoimmune psychosis (AP) patient with anti-NMDAR antibodies. We leveraged publicly available cerebrospinal fluid (C...

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Bibliographic Details
Main Authors: Kwok, AJ, Soleimani, B, Sun, B, Fower, A, Makuch, M, Johnson, T, Knight, JC, Ko, H, Lennox, B, Irani, S, Handunnetthi, L
Format: Internet publication
Language:English
Published: 2024