Functional conservation of HTLV-1 Rex balances the immune pressure for sequence variation in the Rex gene
Naturally occurring mutations in Human T-cell Leukemia Virus Type 1 (HTLV-1) Tax protein lead to loss of recognition by cytotoxic T-lymphocytes. Most of these mutations also abolish or severely impair the transactivation function of Tax. Ninety percent of the <em>Rex</em> gene, which enc...
| Main Authors: | , , , , |
|---|---|
| Format: | Journal article |
| Language: | English |
| Published: |
Elsevier
1997
|
| Subjects: |