Functional conservation of HTLV-1 Rex balances the immune pressure for sequence variation in the Rex gene
Naturally occurring mutations in Human T-cell Leukemia Virus Type 1 (HTLV-1) Tax protein lead to loss of recognition by cytotoxic T-lymphocytes. Most of these mutations also abolish or severely impair the transactivation function of Tax. Ninety percent of the <em>Rex</em> gene, which enc...
| Main Authors: | , , , , |
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| 格式: | Journal article |
| 语言: | English |
| 出版: |
Elsevier
1997
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| 主题: |