Functional conservation of HTLV-1 Rex balances the immune pressure for sequence variation in the Rex gene

Naturally occurring mutations in Human T-cell Leukemia Virus Type 1 (HTLV-1) Tax protein lead to loss of recognition by cytotoxic T-lymphocytes. Most of these mutations also abolish or severely impair the transactivation function of Tax. Ninety percent of the <em>Rex</em> gene, which enc...

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Bibliografiska uppgifter
Huvudupphovsmän: Smith, R, Niewiesk, S, Booth, S, Bangham, C, Daenke, S
Materialtyp: Journal article
Språk:English
Publicerad: Elsevier 1997
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