Targeting tumour hypoxia in breast cancer.
Breast cancer is the most common malignancy in women. Hypoxia occurs in breast cancer and in other solid tumours due to the tumour outgrowing the existing vasculature. Hypoxia leads to an adaptive response, orchestrated by HIF-1 (hypoxia-inducible factor-1), that is crucial for tumour progression an...
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2008
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