Activation of Nrf2-regulated glutathione pathway genes by ischemic preconditioning.
Prophylactic pharmacological activation of astrocytic gene expression driven by the transcription factor Nrf2 boosts antioxidant defences and protects against neuronal loss in ischemia and other disease models. However, the role of Nrf2 in mediating endogenous neuroprotective responses is less clear...
| Main Authors: | , , , , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2011
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