Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

Hepcidin regulates systemic iron homeostasis. Suppression of hepcidin expression occurs physiologically in iron deficiency (ID) and increased erythropoiesis but is pathologic in thalassaemia and haemochromatosis. Here we show that epigenetic events govern hepcidin expression. Erythropoiesis and ID s...

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Bibliographic Details
Main Authors:	Pasricha, S, Lim, P, Duarte, T, Casu, C, Oosterhuis, D, Mleczko-Sanecka, K, Suciu, M, Rita da Silva, A, Al-Hourani, K, Arezes, J, McHugh, K, Gooding, S, Frost, J, Wray, K, Santos, A, Porto, G, Repapi, E, Gray, N, Draper, S, Ashley, N, Soilleux, E, Olinga, P, Muckenthaler, M, Hughes, J, Rivella, S, Milne, T, Armitage, A, Drakesmith, A
Format:	Journal article
Published:	Nature Publishing Group 2017

Hepcidin is regulated by promoter-associated histone acetylation and HDAC3

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