KITD816V induces SRC-mediated tyrosine phosphorylation of MITF and altered transcription program in melanoma
The oncogenic D816V mutation of the KIT receptor is well characterized in systemic mastocytosis and acute myeloid leukemia. Although KIT<sup>D816V</sup> has been found in melanoma, its function and involvement in this malignancy is not understood. Here we show that KIT<sup>D816V<...
| Main Authors: | , , , , , , , , , |
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| Format: | Journal article |
| Published: |
American Association for Cancer Research
2017
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