Treatment of murine osteoarthritis with TrkAd5 reveals a pivotal role for nerve growth factor in non-inflammatory joint pain.

The origin of pain in osteoarthritis is poorly understood, but it is generally thought to arise from inflammation within the innervated structures of the joint, such as the synovium, capsule and bone. We investigated the role of nerve growth factor (NGF) in pain development in murine OA, and the ana...

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Bibliographic Details
Main Authors: McNamee, K, Burleigh, A, Gompels, L, Feldmann, M, Allen, S, Williams, R, Dawbarn, D, Vincent, T, Inglis, J
Format: Journal article
Language:English
Published: 2010