2-Oxoglutarate oxygenases are inhibited by a range of transition metals.

2-Oxoglutarate oxygenases are inhibited by a range of transition metals, as exemplified by studies on human histone demethylases and prolyl hydroxylase domain 2 (PHD2 or EGLN1). The biological effects associated with 2-oxoglutarate oxygenase inhibition may result from inhibition of more than one enz...

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Bibliographic Details
Main Authors: Sekirnik, R, Rose, N, Mecinović, J, Schofield, C
Format: Journal article
Language:English
Published: 2010