Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.

Bibliografiske detaljer
Main Authors:	Ryan, B, Crabtree, M, Channon, K, Wade-Martins, R
Format:	Journal article
Sprog:	English
Udgivet:	2014

Lignende værker

GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
af: Tatham, A, et al.
Udgivet: (2009)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
af: Chuaiphichai, S, et al.
Udgivet: (2014)

Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation
af: Chuaiphichai, S, et al.
Udgivet: (2014)

GTP cyclohydrolase II structure and mechanism.
af: Ren, J, et al.
Udgivet: (2005)

Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
af: Carnicer, R, et al.
Udgivet: (2012)

Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
af: Carnicer, R, et al.
Udgivet: (2012)

303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
af: Chuaiphichai, S, et al.
Udgivet: (2014)

Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.
af: Starr, A, et al.
Udgivet: (2014)

GTP cyclohydrolase I deficiency results in oxidative stress and pulmonary hypertension
af: Khoo, J, et al.
Udgivet: (2004)

Cardiomyocyte-Targeted Overexpression of GTP Cyclohydrolase-1 Increases Myocyte Lusitropy and Reduces Superoxide Production
af: Carnicer, R, et al.
Udgivet: (2010)

GTP cyclohydrolase as a novel mechanism for tumour growth
af: Chen, L, et al.
Udgivet: (2015)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
af: Adlam, D, et al.
Udgivet: (2012)

Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin
af: Adlam, D, et al.
Udgivet: (2012)

Endotoxemia-related acute kidney injury in transgenic mice with endothelial overexpression of GTP cyclohydrolase-1.
af: Wang, W, et al.
Udgivet: (2008)

Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
af: Carnicer, R, et al.
Udgivet: (2011)

Endothelial-specific GTP cyclohydrolase overexpression reduces blood pressure in salt-sensitive hypertension
af: Chen, A, et al.
Udgivet: (2006)

Decreased Cardiac Allograft Rejection in Mice Over-Expressing Human GTP Cyclohydrolase I.
af: Irina, I, et al.
Udgivet: (2009)

Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
af: Chuaiphichai, S, et al.
Udgivet: (2021)

Genetic variation in GCH1, encoding GTP-cyclohydrolase 1, regulates biopterin levels and endothelial function in atherosclerosis
af: Van, A, et al.
Udgivet: (2008)

Tetrahydrobiopterin- and glutathionylation-dependent regulation of eNOS coupling: Relationships revealed by eNOS glutathionylation mutants in cells with tet-regulated GTP cyclohydrolase I expression
af: Crabtree, M, et al.
Udgivet: (2012)

Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.
af: Hussein, D, et al.
Udgivet: (2015)

Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk.
af: Doehring, A, et al.
Udgivet: (2008)

Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.
af: Liao, S, et al.
Udgivet: (2007)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
af: Du, Y, et al.
Udgivet: (2005)

Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
af: Du, Y, et al.
Udgivet: (2005)

Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
af: Alp, N, et al.
Udgivet: (2002)

Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension
af: Chen, A, et al.
Udgivet: (2005)

GTP cyclohydrolase 1 gene transfer increases nitric oxide synthesis in endothelial cells and isolated vessels from type I and type II diabetic
af: Meininger, C, et al.
Udgivet: (2004)

GTP Cyclohydrolase/BH4 Pathway Protects EPC Function via Suppressing Oxidative Stress and Thrombospondin-1 in Salt-Sensitive Hypertension
af: Xie, H, et al.
Udgivet: (2009)

Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
af: Fernandes, H, et al.
Udgivet: (2017)

α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease.
af: Ryan, B, et al.
Udgivet: (2014)

GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1.
af: Tie, L, et al.
Udgivet: (2014)

Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
af: Alp, N, et al.
Udgivet: (2003)

Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes.
af: Tie, L, et al.
Udgivet: (2009)

Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
af: Chen, A, et al.
Udgivet: (2005)

GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner
af: Wang, Z, et al.
Udgivet: (2023)

GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension
af: Xie, H, et al.
Udgivet: (2010)

GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension.
af: Xie, H, et al.
Udgivet: (2010)

Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection.
af: Ionova, I, et al.
Udgivet: (2010)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
af: Alp, N, et al.
Udgivet: (2003)