Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.

Parkinson's disease in GTP cyclohydrolase 1 mutation carriers.

Bibliografiset tiedot
Päätekijät:	Ryan, B, Crabtree, M, Channon, K, Wade-Martins, R
Aineistotyyppi:	Journal article
Kieli:	English
Julkaistu:	2014

Samankaltaisia teoksia

GTP cyclohydrolase I expression, protein, and activity determine intracellular tetrahydrobiopterin levels, independent of GTP cyclohydrolase feedback regulatory protein expression.
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Cell-autonomous role of endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
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Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
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Cardiomyocyte GTP cyclohydrolase 1 and tetrahydrobiopterin increase NOS1 activity and accelerate myocardial relaxation
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303A cell-Autonomous role for endothelial GTP cyclohydrolase 1 and tetrahydrobiopterin in blood pressure regulation.
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Overexpression of GTP cyclohydrolase 1 feedback regulatory protein is protective in a murine model of septic shock.
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GTP cyclohydrolase I deficiency results in oxidative stress and pulmonary hypertension
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Cardiomyocyte-Targeted Overexpression of GTP Cyclohydrolase-1 Increases Myocyte Lusitropy and Reduces Superoxide Production
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GTP cyclohydrolase as a novel mechanism for tumour growth
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Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin.
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Regulation of β-adrenergic control of heart rate by GTP-cyclohydrolase 1 (GCH1) and tetrahydrobiopterin
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Endotoxemia-related acute kidney injury in transgenic mice with endothelial overexpression of GTP cyclohydrolase-1.
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Cardiomyocyte-targeted overexpression of GTP cyclohydrolase-1 increases nNOS activity and hastens myocardial relaxation
Tekijä: Carnicer, R, et al.
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Endothelial-specific GTP cyclohydrolase overexpression reduces blood pressure in salt-sensitive hypertension
Tekijä: Chen, A, et al.
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Decreased Cardiac Allograft Rejection in Mice Over-Expressing Human GTP Cyclohydrolase I.
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Endothelial GTP cyclohydrolase and tetrahydrobiopterin regulate gestational blood pressure, uteroplacental remodeling and fetal growth
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Genetic variation in GCH1, encoding GTP-cyclohydrolase 1, regulates biopterin levels and endothelial function in atherosclerosis
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Tetrahydrobiopterin- and glutathionylation-dependent regulation of eNOS coupling: Relationships revealed by eNOS glutathionylation mutants in cells with tet-regulated GTP cyclohydrolase I expression
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Validating the GTP-cyclohydrolase 1-feedback regulatory complex as a therapeutic target using biophysical and in vivo approaches.
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Clinical genetics of functionally mild non-coding GTP cyclohydrolase 1 (GCH1) polymorphisms modulating pain and cardiovascular risk.
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Endothelium-targeted transgenic GTP-cyclohydrolase I overexpression inhibits neointima formation in mouse carotid artery.
Tekijä: Liao, S, et al.
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Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension
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Endothelial-targeted GTP cyclohydrolase I overexpression prevents blood pressure progression in mineralocorticoid hypertension\
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Systemic adenovirus-mediated gene transfer of human GTP cyclohydrolase-1 increases liver, plasma and aortic tetrahydrobiopterin levels in mice
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Endothelial-specific GTP cyclohydrolase I overexpression prevents blood pressure progression in salt-sensitive hypertension
Tekijä: Chen, A, et al.
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GTP cyclohydrolase 1 gene transfer increases nitric oxide synthesis in endothelial cells and isolated vessels from type I and type II diabetic
Tekijä: Meininger, C, et al.
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GTP Cyclohydrolase/BH4 Pathway Protects EPC Function via Suppressing Oxidative Stress and Thrombospondin-1 in Salt-Sensitive Hypertension
Tekijä: Xie, H, et al.
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Commentary: Parkinson disease-linked GBA mutation effects reversed by molecular chaperones in human cell and fly models
Tekijä: Fernandes, H, et al.
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α-Synuclein and mitochondrial bioenergetics regulate tetrahydrobiopterin levels in a human dopaminergic model of Parkinson disease.
Tekijä: Ryan, B, et al.
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GTP cyclohydrolase I prevents diabetic-impaired endothelial progenitor cells and wound healing by suppressing oxidative stress/thrombospondin-1.
Tekijä: Tie, L, et al.
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Nitric oxide Bioavailability is preserved in diabetes by increased endothelial tetrahydrobiopterin synthesis in targeted GTP cyclohydrolase transgenic mice
Tekijä: Alp, N, et al.
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Endothelium-specific GTP cyclohydrolase I overexpression accelerates refractory wound healing by suppressing oxidative stress in diabetes.
Tekijä: Tie, L, et al.
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Endothelium-targeted GTP cyclohydrolase I overexpression inhibits wire injury-induced restenosis in mouse carotid artery
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GTP cyclohydrolase drives breast cancer development and promotes EMT in an enzyme-independent manner
Tekijä: Wang, Z, et al.
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GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension
Tekijä: Xie, H, et al.
Julkaistu: (2010)

GTP cyclohydrolase I/BH4 pathway protects EPCs via suppressing oxidative stress and thrombospondin-1 in salt-sensitive hypertension.
Tekijä: Xie, H, et al.
Julkaistu: (2010)

Cardiac myocyte-specific overexpression of human GTP cyclohydrolase I protects against acute cardiac allograft rejection.
Tekijä: Ionova, I, et al.
Julkaistu: (2010)

Nitric oxide bioactivity in ApoE -/- mice is maintained by increased endothelial tetrahydrobiopterin synthesis via targeted GTP cyclohydrolase-1 over-expression
Tekijä: Alp, N, et al.
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