Widespread hypoxia-inducible expression of HIF-2alpha in distinct cell populations of different organs.

Cellular responses to oxygen are increasingly recognized as critical in normal development and physiology, and are implicated in pathological processes. Many of these responses are mediated by the transcription factors HIF-1 and HIF-2. Their regulation occurs through oxygen-dependent proteolysis of...

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Bibliographic Details
Main Authors: Wiesener, MS, Jürgensen, J, Rosenberger, C, Scholze, C, Hörstrup, J, Warnecke, C, Mandriota, S, Bechmann, I, Frei, U, Pugh, C, Ratcliffe, P, Bachmann, S, Maxwell, P, Eckardt, K
Format: Journal article
Language:English
Published: 2003