Bifunctional iminophosphorane catalyzed enantioselective ketimine phospha-Mannich reaction

The enantioselective phospha-Mannich reaction of diethyl phosphite to unactivated N-DPP-protected ketimines catalyzed by a bifunctional iminophosphorane (BIMP) superbase organocatalyst is described. The reaction is applicable to ketimines bearing electron-rich and electron-poor aryl substituents and...

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Bibliographic Details
Main Authors: Robertson, G, Farley, A, Dixon, D
Format: Journal article
Published: Thieme Publishing 2015