Investigating DNA double-strand break repair in Dictyostelium discoideum

<p>DNA double-strand breaks (DSBs) are toxic lesions that can be repaired by numerous mechanistically distinct pathways. However, regulation of DSB repair pathway utilisation is also essential for maintaining genomic integrity, and eukaryotes have evolved several mechanisms to achieve this. T...

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Bibliographic Details
Main Author: Couto, C
Other Authors: Lakin, N
Format: Thesis
Language:English
Published: 2011
Subjects: