The alpha-glucosidase inhibitor N-butyldeoxynojirimycin inhibits human immunodeficiency virus entry at the level of post-CD4 binding.

The alpha-glucosidase inhibitor N-butyldeoxynojirimycin (NB-DNJ) is a potent inhibitor of human immunodeficiency virus (HIV) replication and syncytium formation in vitro. However, the exact mechanism of action of NB-DNJ remains to be determined. In this study we have examined the impairment of HIV i...

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Bibliographic Details
Main Authors: Fischer, P, Collin, M, Karlsson, G, James, W, Butters, T, Davis, S, Gordon, S, Dwek, R, Platt, F
Format: Journal article
Language:English
Published: 1995