Influences on the design and purification of soluble, recombinant native-like HIV-1 envelope glycoprotein trimers

We have investigated factors that influence the production of native-like soluble, recombinant trimers based on the env genes of two isolates of human immunodeficiency virus type 1 (HIV-1), specifically 92UG037.8 (clade A) and CZA97.012 (clade C). When the recombinant trimers based on the env genes...

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Bibliographic Details
Main Authors: Ringe, R, Yasmeen, A, Ozorowski, G, Go, E, Pritchard, L, Guttman, M, Ketas, T, Cottrell, C, Wilson, I, Sanders, R, Cupo, A, Crispin, M, Lee, K, Desaire, H, Ward, A, Klasse, P, Moore, J
Format: Journal article
Published: American Society for Microbiology 2015