Pharmacokinetic investigation of the interaction of azapropazone with phenytoin.

We have investigated the interaction of azapropazone with phenytoin in five healthy volunteers. From steady-state plasma phenytoin concentrations of about 17 mumol/l there was at least a two-fold increase following the introduction of azapropazone. The main mechanism of the interaction was a decreas...

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Bibliografiska uppgifter
Huvudupphovsmän: Geaney, D, Carver, J, Davies, C, Aronson, J
Materialtyp: Journal article
Språk:English
Publicerad: 1983