Toll-like receptor 7 protects from atherosclerosis by constraining "inflammatory" macrophage activation.

BACKGROUND: Toll-like receptors (TLRs) have long been considered to be major culprits in the development of atherosclerosis, contributing both to its progression and clinical complications. However, evidence for most TLRs beyond TLR2 and TLR4 is lacking. METHODS AND RESULTS: We used experimental mo...

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Bibliographic Details
Main Authors: Salagianni, M, Galani, I, Lundberg, A, Davos, C, Varela, A, Gavriil, A, Lyytikäinen, L, Lehtimäki, T, Sigala, F, Folkersen, L, Gorgoulis, V, Lenglet, S, Montecucco, F, Mach, F, Hedin, U, Hansson, G, Monaco, C, Andreakos, E
Format: Journal article
Language:English
Published: 2012