In vitro mycobacterial growth inhibition assays: A tool for the assessment of protective immunity and evaluation of tuberculosis vaccine efficacy

Tuberculosis (TB) continues to pose a serious global health threat, and the current vaccine, BCG, has variable efficacy. However, the development of a more effective vaccine is severely hampered by the lack of an immune correlate of protection. Candidate vaccines are currently evaluated using precli...

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Bibliographic Details
Main Authors: Mcshane, H, Tanner, R, O'Shea, M, Fletcher, H
Format: Journal article
Published: Elsevier 2017