In vitro mycobacterial growth inhibition assays: A tool for the assessment of protective immunity and evaluation of tuberculosis vaccine efficacy

In vitro mycobacterial growth inhibition assays: A tool for the assessment of protective immunity and evaluation of tuberculosis vaccine efficacy

Tuberculosis (TB) continues to pose a serious global health threat, and the current vaccine, BCG, has variable efficacy. However, the development of a more effective vaccine is severely hampered by the lack of an immune correlate of protection. Candidate vaccines are currently evaluated using precli...

पूर्ण विवरण

ग्रंथसूची विवरण
मुख्य लेखकों:	Mcshane, H, Tanner, R, O'Shea, M, Fletcher, H
स्वरूप:	Journal article
प्रकाशित:	Elsevier 2017

समान संसाधन

Tools for assessing the protective efficacy of TB vaccines in humans: in vitro mycobacterial growth inhibition predicts outcome of in vivo mycobacterial infection
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2020)

The influence of haemoglobin and iron on in vitro mycobacterial growth inhibition assays
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2017)

The in vitro direct mycobacterial growth inhibition assay (MGIA) for the early evaluation of TB vaccine candidates and assessment of protective immunity: a protocol for non-human primate cells
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2021)

A new tool for tuberculosis vaccine screening: Ex vivo Mycobacterial Growth Inhibition Assay indicates BCG mediated protection in a murine model of tuberculosis
द्वारा: McShane, H, और अन्य
प्रकाशित: (2016)

A mycobacterial growth inhibition assay (MGIA) for bovine TB vaccine development
द्वारा: Pepponi, I, और अन्य
प्रकाशित: (2017)

Development and application of the direct mycobacterial growth inhibition assay: a systematic review
द्वारा: Painter, H, और अन्य
प्रकाशित: (2024)

Evaluating the effect of BCG vaccination on a whole-blood mycobacterial growth inhibition assay (BACTEC MGIT)
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2011)

Immunological correlates of mycobacterial growth inhibition describe a spectrum of tuberculosis infection
द्वारा: O'Shea, M, और अन्य
प्रकाशित: (2018)

Demonstrating the utility of the ex vivo murine mycobacterial growth inhibition assay (MGIA) for high-throughput screening of tuberculosis vaccine candidates against multiple Mycobacterium tuberculosis complex strains
द्वारा: Painter, H, और अन्य
प्रकाशित: (2024)

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb).
द्वारा: Marsay, L, और अन्य
प्रकाशित: (2013)

Mycobacterial growth inhibition in murine splenocytes as a surrogate for protection against Mycobacterium tuberculosis (M. tb)
द्वारा: Marsay, L, और अन्य
प्रकाशित: (2013)

Inhibition of mycobacterial growth in vitro following primary but not secondary vaccination with Mycobacterium bovis BCG.
द्वारा: Fletcher, H, और अन्य
प्रकाशित: (2013)

Human hookworm infection enhances mycobacterial growth inhibition and associates with reduced risk of tuberculosis infection
द्वारा: O'Shea, M, और अन्य
प्रकाशित: (2018)

The characterisation of mycobacterial control profiles and underlying immune signatures in patients with latent tuberculosis infection and active disease
द्वारा: O'Shea, M
प्रकाशित: (2016)

Development of mycobacterial growth inhibition assays for the early evaluation and gating of novel TB vaccine candidates
द्वारा: Tanner, R
प्रकाशित: (2015)

The cross-species mycobacterial growth inhibition assay (MGIA) project 2010-2014
द्वारा: Brennan, M, और अन्य
प्रकाशित: (2017)

Co-immunization with DNA vaccines expressing granulocyte-macrophage colony-stimulating factor and mycobacterial secreted proteins enhances T-cell immunity, but not protective efficacy against Mycobacterium tuberculosis.
द्वारा: Kamath, A, और अन्य
प्रकाशित: (1999)

Assessment of the reproducibility and inter-site transferability of the murine direct splenocyte mycobacterial growth inhibition assay (MGIA)
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2021)

Adaption of the ex vivo mycobacterial growth inhibition assay for use with murine lung cells
द्वारा: Painter, H, और अन्य
प्रकाशित: (2020)

Tuberculosis vaccine promises sterilizing immunity.
द्वारा: Mcshane, H, और अन्य
प्रकाशित: (2011)

Process of Assay Selection and Optimization for the Study of Case and Control Samples from a Phase IIb Efficacy Trial of a Candidate Tuberculosis Vaccine, MVA85A
द्वारा: Harris, SA, और अन्य
प्रकाशित: (2014)

Correlates of immune protection from tuberculosis.
द्वारा: Fletcher, H
प्रकाशित: (2007)

Optimisation, harmonisation and standardisation of the direct mycobacterial growth inhibition assay using cryopreserved human peripheral blood mononuclear cells
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2019)

A non-human primate in vitro functional assay for the early evaluation of TB vaccine candidates
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2021)

Distinct transcriptional and anti-mycobacterial profiles of peripheral blood monocytes dependent on the ratio of monocytes: lymphocytes
द्वारा: Naranbhai, V, और अन्य
प्रकाशित: (2015)

Tuberculosis vaccines: current status and future prospects.
द्वारा: Fletcher, H, और अन्य
प्रकाशित: (2006)

Vaccines for tuberculosis
द्वारा: McShane, H
प्रकाशित: (2013)

Understanding vaccine induced protective immunity to Mycobacterium tuberculosis
द्वारा: Ronan, E
प्रकाशित: (2011)

Tuberculin skin testing and treatment modulates interferon-gamma release assay results for latent tuberculosis in migrants
द्वारा: O'Shea, M, और अन्य
प्रकाशित: (2014)

Identification of novel mycobacterial antigens presented by MHC-I and -II by immunopeptidomics for vaccines against tuberculosis
द्वारा: Bettencourt, P, और अन्य
प्रकाशित: (2019)

A New Vaccine for Tuberculosis: The Challenges of Development and Deployment
द्वारा: Fletcher, H, और अन्य
प्रकाशित: (2009)

Replacing, reducing and refining the use of animals in tuberculosis vaccine 1 research
द्वारा: Tanner, R, और अन्य
प्रकाशित: (2016)

Immunogenicity and protective efficacy of mycobacterial DNA vaccines incorporating plasmid-encoded cytokines against Mycobacterium bovis.
द्वारा: Young, S, और अन्य
प्रकाशित: (2010)

Vaccine strategies against tuberculosis.
द्वारा: Mcshane, H
प्रकाशित: (2009)

Inflammation and immune activation are associated with risk of Mycobacterium tuberculosis infection in BCG-vaccinated infants
द्वारा: Satti, I, और अन्य
प्रकाशित: (2022)

Cholera toxin enhances vaccine-induced protection against Mycobacterium tuberculosis challenge in mice
द्वारा: Griffiths, K, और अन्य
प्रकाशित: (2013)

Current approaches toward identifying a correlate of immune protection from tuberculosis
द्वारा: Satti, I, और अन्य
प्रकाशित: (2018)

Regulation of mycobacterial infection by macrophage Gch1 and tetrahydrobiopterin
द्वारा: McNeill, E, और अन्य
प्रकाशित: (2018)

Mycobacterial blood culture for diagnosis of tuberculosis in Vietnamese children
द्वारा: Tran, S, और अन्य
प्रकाशित: (2019)

Tuberculosis vaccines in clinical trials.
द्वारा: Rowland, R, और अन्य
प्रकाशित: (2011)