Unusual molecular architecture of the machupo virus attachment glycoprotein

New World arenaviruses, which cause severe hemorrhagic fever, rely upon their envelope glycoproteins for attachment and fusion into their host cell. Here we present the crystal structure of the Machupo virus GP1 attachment glycoprotein, which is responsible for high-affinity binding at the cell surf...

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Bibliographic Details
Main Authors: Bowden, T, Crispin, M, Graham, S, Harvey, D, Grimes, J, Jones, E, Stuart, D
Format: Journal article
Language:English
Published: American Society for Microbiology 2009