Bisphosphonate treatment of aggressive primary, recurrent and metastatic Giant Cell Tumour of Bone.

BACKGROUND: Giant cell tumour of bone (GCTB) is an expansile osteolytic tumour which contains numerous osteoclast-like giant cells. GCTB frequently recurs and can produce metastatic lesions in the lungs. Bisphosphonates are anti-resorptive drugs which act mainly on osteoclasts. METHOD: In this stud...

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Bibliographic Details
Main Authors: Balke, M, Campanacci, L, Gebert, C, Picci, P, Gibbons, M, Taylor, R, Hogendoorn, P, Kroep, J, Wass, J, Athanasou, N
Format: Journal article
Language:English
Published: BioMed Central 2010