Monitoring base excision repair proteins on damaged DNA using human cell extracts.
BER (base excision repair) is a major pathway for the removal of simple lesions in DNA including base damage and base loss (abasic site). We have developed an assay, using formaldehyde cross-linking during repair in human cell extracts, to observe BER proteins involved in the repair of damaged DNA....
| Main Authors: | , |
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| Format: | Journal article |
| Language: | English |
| Published: |
2004
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