Spirocyclic tetramates by sequential Knoevenagel and [1,5]-prototropic shift

Highly functionalised spirocyclic tetramates were prepared via tert-amino reaction of bicyclic tetramates. While these compounds isomerise in solution, stable analogues can be prepared via appropriate choice of substituents. Further modification of these compounds allows for introduction of aromatic...

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Bibliographic Details
Main Authors: Josa-Culleré, L, Hirst, MG, Lockett, JP, Thompson, AL, Moloney, MG
Format: Journal article
Language:English
Published: American Chemical Society 2019