Enhanced detection of human immunodeficiency virus type 1-specific T-cell responses to highly variable regions by using peptides based on autologous virus sequences.

The antigenic diversity of human immunodeficiency virus type 1 (HIV-1) represents a significant challenge for vaccine design as well as the comprehensive assessment of HIV-1-specific immune responses in infected persons. In this study we assessed the impact of antigen variability on the characteriza...

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Bibliographic Details
Main Authors: Altfeld, M, Addo, M, Shankarappa, R, Lee, P, Allen, T, Yu, X, Rathod, A, Harlow, J, O'Sullivan, K, Johnston, M, Goulder, P, Mullins, J, Rosenberg, E, Brander, C, Korber, B, Walker, B
Format: Journal article
Language:English
Published: 2003