NR4A nuclear receptors target Poly-ADP-Ribosylated DNA-PKcs protein to promote DNA repair

Although poly-ADP-ribosylation (PARylation) of DNA repair factors had been well documented, its role in the repair of DNA double-strand breaks (DSBs) is poorly understood. NR4A nuclear orphan receptors were previously linked to DSB repair; however, their function in the process remains elusive. Clas...

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Bibliographic Details
Main Authors: Munnur, D, Somers, J, Skalka, G, Weston, R, Jukes-Jones, R, Bhogadia, M, Dominguez, C, Cain, K, Ahel, I, Malewicz, M
Format: Journal article
Language:English
Published: Elsevier 2019