Structural basis for antibiotic transport and inhibition in PepT2
The uptake and elimination of beta-lactam antibiotics in the human body are facilitated by the proton-coupled peptide transporters PepT1 (SLC15A1) and PepT2 (SLC15A2). The mechanism by which SLC15 family transporters recognize and discriminate between different drug classes and dietary peptides rema...
Główni autorzy: | , , , , , , |
---|---|
Format: | Journal article |
Język: | English |
Wydane: |
Nature Research
2024
|