Structural basis for antibiotic transport and inhibition in PepT2

The uptake and elimination of beta-lactam antibiotics in the human body are facilitated by the proton-coupled peptide transporters PepT1 (SLC15A1) and PepT2 (SLC15A2). The mechanism by which SLC15 family transporters recognize and discriminate between different drug classes and dietary peptides rema...

Szczegółowa specyfikacja

Opis bibliograficzny
Główni autorzy: Parker, JL, Deme, JC, Lichtinger, SM, Kuteyi, G, Biggin, PC, Lea, SM, Newstead, S
Format: Journal article
Język:English
Wydane: Nature Research 2024