A bacterial artificial chromosome reporter system for expression of the human FOXP3 gene in mouse regulatory T-cells.

The transcription factor FOXP3 plays key roles in the development and function of regulatory T cells (Treg) capable of preventing and correcting immunopathology. There has been much interest in exploiting Treg as adoptive cell therapy in man, but issues of lack of nominal antigen-specificity and sta...

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Váldodahkkit: Tsuda, M, Tone, Y, Ogawa, C, Nagaoka, Y, Katsumata, M, Necula, A, Howie, D, Masuda, E, Waldmann, H, Tone, M
Materiálatiipa: Journal article
Giella:English
Almmustuhtton: Frontiers Media 2017