A bacterial artificial chromosome reporter system for expression of the human FOXP3 gene in mouse regulatory T-cells.
The transcription factor FOXP3 plays key roles in the development and function of regulatory T cells (Treg) capable of preventing and correcting immunopathology. There has been much interest in exploiting Treg as adoptive cell therapy in man, but issues of lack of nominal antigen-specificity and sta...
Váldodahkkit: | , , , , , , , , , |
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Materiálatiipa: | Journal article |
Giella: | English |
Almmustuhtton: |
Frontiers Media
2017
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