Molecular and structural analysis of a continuous birch profilin epitope defined by a monoclonal antibody.

The interaction of a mouse monoclonal antibody (4A6) and birch profilin, a structurally well conserved actin- and phosphoinositide-binding protein and cross-reactive allergen, was characterized. In contrast to serum IgE from allergic patients, which shows cross-reactivity with most plants, monoclona...

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Bibliographic Details
Main Authors: Wiedemann, P, Giehl, K, Almo, S, Fedorov, A, Girvin, M, Steinberger, P, Rüdiger, M, Ortner, M, Sippl, M, Dolecek, C, Kraft, D, Jockusch, B, Valenta, R
Format: Journal article
Language:English
Published: 1996