Initial assessment of a model relating intratumoral genetic heterogeneity to radiological morphology.

Tumour heterogeneity has major implications for tumour development and response to therapy. Tumour heterogeneity results from mutations in the genes responsible for mismatch repair or maintenance of chromosomal stability. Cells with different genetic properties may grow at different rates and exhibi...

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Bibliographic Details
Main Authors: Noterdaeme, O, Kelly, M, Friend, P, Soonowalla, Z, Steers, G, Brady, M
Format: Journal article
Language:English
Published: 2010